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Bioerrorism, Physician Education, and the Internet

    In the United States meeting the challenge of effectively managing domestic bioterrorism using infectious agents is a new issue for our country as a whole and for the civilian health care sector in particular. Individually practicing physicians and nurses need to consider four issues if they are to effectively meet these bioterorrism challenges.

bulletThe early symptoms of diseases caused by bioterrorism can mimic those of much more common aliments and early, specific treatment can be life saving. The knowledge that a previously rare disease is present can be useful in making the correct diagnosis. Therefore early responders such as police, fire and EMS personnel, physicians and nurses need to have current, ongoing information about bioterrorism occurrences. Because of travel and our nation-wide mail system this information should cover both local and national outbreaks.

bulletThe basic science and clinical knowledge to appropriately triage, diagnosis, and treat suspected patients is necessary. Immunization strategies and the appropriate prophylactic treatment of contacts are likewise important.
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bulletIf one has a patient that could have an illness or death related to a bioterrorist act the appropriate public health authorities need to be notified promptly.

bulletHealth care providers should be aware of and make recommendations if needed with respect to community resources that can be mobilized to address bioterrorism.

    The web is a uniquely well positioned source to fulfill these informational and educational requirements as long as reliable Internet sources are accessed. Particulars about new or different outbreaks can be rapidly disseminated at relatively little expense. Tutorial materials that contain text, images and audio can be made readily available. Government, university, and medical organizations have web pages devoted to bioterrorism and physician education. Web category one continuing medical education credits on issues addressing bioterrorism are now being offered.  To be included as references in this paper sites had have peer reviewed, evidenced-based sources of information, document authorship, be timely updated, and be freely available on the Internet. 


Medical Web Sites

American Medical Association Physician Resource Center on Terrorism

   This AMA resource center is divided into biological, radiological, and chemical sections which deal with these three aspects of terrorism, and a fourth section which addressees the issue of preparedness. Each of the four areas lists germane organizations with have expertise in the respective areas. 

AMA Consensus and Update Articles

    JAMA and the Archives have published a variety of articles on bioterrorism and the AMA is making many of these articles available in the full text version to the public free of charge. The six consensus articles on bioterrorism by the Working Group on Civilian Biodefense address  anthrax, botulinum toxin, hemorrhagic fever, plague, smallpox, and tularemia. Each article gives in depth information about their respective diseases.  Updates are published as needed and the  anthrax consensus statement was revised in May 2002.

    Although  not a bioterrorism tool the nerve agent Sarin is discussed in detail  and tables for the treatment for Nerve Agents (Tabun, Sarin, Soman, and VX ) are presented in the JAMA article: Clinical Manifestations of Sarin Nerve Gas Exposure


 

 

Association for Professionals in Infection Control and Epidemiology 

    APIC is a non-profit international organization dedicated to providing communication and education for persons involved in infection control activities.  It has a section devoted to bioterrorism that lists resources including handbooks, preparedness guidelines,  and wall posters dealing with this topic.


 

 

 

Center for Disease Control (CDC) bioterrorism pages


CDC’s 24/7 Emergency Ops Center for physicians and health care providers is at (770) 488-7100 or (770) 488-4819

    This is the CDC directory for information on bioterrorism issues. It has a wide audience as it is directed to the general public, providers, and public health officials. For physicians the Agents and Disease page contains detailed information or direct links to disease/agent specific information. Items such as case definitions, treatment recommendations, and isolation guidelines can be found. Both biological and chemical agents are referenced. Emphasis is placed on Category A diseases. CDC defines them as agents that pose a risk to national security because they can be easily disseminated or transmitted person-to-person; cause high mortality; have the potential for major public health impact; might cause public panic and social disruption; and require special action for public health preparedness. The five diseases in this category are Bacillus anthracis (anthrax) Clostridium botulinum toxin (botulism) Yersinia pestis (plague) variola major (smallpox) and Francisella tularensis (tularemia). Class B and C diseases are also discussed and there is a section devoted to chemical agents.

 

 


CDC Health Alert Network


    The Health Alert Network is being developed as part of CDC's Public Health Emergency Preparedness & Response Program. It is updated as needed on a daily basis and contains the latest news with respect to bioterrorism. Timely communication to health care providers, education, and reporting mechanisms are the goal of this site. Web casts on anthrax, and the latest treatment recommendations are included. There is a link to report to CDC any incidents that may be related to bioterrorism.



The CDC Morbidity and Mortality Weekly Report (MMWR)


    This is a particularly valuable reference for a variety of reasons. It contains practical evidence based information, and the guidelines for dealing with a particular disease such as antibiotic protocols and isolation recommendations. MMWR represents the current thinking of infection control experts. The CDC is a de-facto clearing house for bioterrorism incidents and combining this with MMWR’s weekly publication dates generates timely information. Although MMWR is reprinted in JAMA there is generally a significant delay. The October 25, 2001 MMWR chronicling the anthrax threat was published in the November 14 issue of JAMA


 

Electronic Textbook of Dermatology

    The chapter on Biological Warfare and its Cutaneous Manifestations has short discussions and photos of a number of the dermatological manifestations of conditions such as anthrax, bubonic plague, tularemia, and smallpox. Clicking on the photos embedded in the text will enlarge them.

 

 

 

 

Medcscape Bioterorism Resource Center

    To access some of the resources on Medscape you need to register.

    This center contains links to timely news and reference material about potential bioterrorism agents and recognizing their clinical signs and symptoms. There is also a section on CMEs dealing with this subject, and the CDCs Public Response Hotline (888) 246-2675 is posted.

    Also on the Medscape Web site is the Journal Neurosurgical Focus.  Volume 12, 3 from 2002 is devoted in large part to weapons of mass destruction. While directed toward neurosurgeons much of what is discussed is useful to any physician who is interested in or may have to deal with such events. There are five articles:

bulletTriage for the Neurosurgeon

bulletWeapons of Mass Destruction: Radiation

bulletCommon Chemical Agent Threats

bulletWeapons of Mass Destruction: Biological

bulletThreat Credibility and Weapons of Mass Destruction.


 

 


United States Army Medical Research Institute of Infectious Diseases (USAMRIID)

    The primary focus of USAMRIID is bioterrorism protection in the context of military operations. However much of what it does and its laboratories are germane to bioterrorism in the civilian sector. There are liaisons between it and CDC, the World Health Organization and academic medical centers. It has expertise in investigating infectious diseases that require special containment, and formulates strategies, procedures, and training programs for medical defense against biological threats.

    At its web site there is a section on programs it sponsors and educational tools dealing with bioterrorism. Some of these resources are available to the civilian sector and the book USAMRIID's MEDICAL MANAGEMENT  OF BIOLOGICAL CASUALTIES HANDBOOK Fifth Edition, August 2004 can be downloaded at no charge.  An ER could put it on their computer and quickly go from section to section. For the various diseases and chemical agents one can obtain a succinct summary covering important information such as isolation recommendations, diagnostic criteria, and treatment protocols. 

 

 


Mass Media Web sites


    A national newspaper or mass media site plus a regional paper is a valuable resource for very timely, general information. At the national level The New York Times   and CNN  will have any late breaking stories on bioterrorism.

 

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This page was last updated on 08/08/05